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. 2020 Jan 7;26(1):86–96. doi: 10.3748/wjg.v26.i1.86

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Serum microRNA-122 level in correlation to Child-Pugh score, Barcelona clinic liver cancer stage and underlying etiology. A: Serum microRNA-122 (miR-122) level in relation to Child-Pugh score: No liver cirrhosis (n = 16), class A (n = 45), class B (n = 27), and class C (n = 3); B: Serum miR-122 level in relation to Barcelona clinic liver cancer staging system: Stage A (n = 16), stage B (n = 37), stage C (n = 32), and stage D (n = 6); C: Serum miR-122 level in relation to underlying etiology of the hepatocellular carcinoma: Alcohol abuse (n = 41), viral hepatitis (n = 12), non-alcoholic steatohepatitis (n = 13), hemochromatosis (n = 6), rare or other (n = 19). Kruskal-Wallis test and post-hoc Dunn’s test were used for statistical analysis. LC: Liver cirrhosis; NASH: Non-alcoholic steatohepatitis; BCLC: Barcelona clinic liver cancer.