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. 2019 Jan 11;17(1):85–94. doi: 10.1038/s41423-018-0195-8

Fig. 6.

Fig. 6

Effects of the overexpression of HSP70L1 and DNAJC2 on the H2AK119Ub1, H3K4me3, and H3K27me3 modifications of the CD40, CD86, HLA-DR, and STAT3 promoters in MoDCs at early stage. ChIP analysis of the H2AK119Ub1, H3K4me3, and H3K27me3 modifications on the CD40, CD86, HLA-DR, and STAT3 promoter regions after 48 h of MoDCs transfected with AdCtrl, AdDNAJC2, or AdHSP70L1 on day 1. Data are normalized to input and then control IgG is set as 1. Data are shown as the mean ± s.d. of three determinants in one ChIP experiment. Representative results of three independent experiments are shown. *p < 0.05, **p < 0.01, ***p < 0.001 compared to AdCtrl group (t test)