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. 2020 Jan 9;3:20. doi: 10.1038/s42003-019-0747-1

Fig. 3. Visualization of increased lacunar density in femoral cortices of STZ group.

Fig. 3

a–d Representative scanning electron microscopy (SEM) and e–h H&E-stained histology images, i quantification of osteocyte lacuna number in the SEM images in a–d, j quantification of osteocyte lacuna number in the histology images in e–h, k illustration of increased cellular density in the femur cortices of STZ group. In both SEM and histology images, femoral cortices of STZ group appeared more cellular than the euglycemic group (white arrows indicate osteocyte lacunae, two-way ANOVA and post-hoc Newman–Keuls for i, Student’s t-test for j, mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001, n = 3 animals, scale bars represent 100 μm (a–d, g, h) and 300 µm (e, f)).