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. 2020 Jan 9;10:64. doi: 10.1038/s41598-019-56896-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Chediak-Higashi syndrome in cats at 5.5 months of age. A symptom of Chediak-Higashi syndrome, the affected cat (left) has a much lighter coat color (hypopigmentation) than its non-affected littermate (right). Although both cats are genetically aaB-C-D-E-I-ll, the genotype for a solid black smoke longhaired cat. The affected cat is also photophobic and has pale yellow-green irises, instead of the normal copper color irises of its littermate.