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. 2020 Jan 9;10:64. doi: 10.1038/s41598-019-56896-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pedigree of resurrected feline model of Chediak-Higashi syndrome via assisted reproduction. Half-filled symbols in pedigree represent predicted carrier status based on presence of the mutant allele from genotyping. The founder male Smokey (arrow) is heterozygous, as he did not present with CHS-associated symptoms throughout his life. The founder females, 12OTHN2 and 12ODH5, likely do not carry NM_001290242.1:c.8347-2422_9548 + 1749dup as these females were from a commercial breeding colony of cats. Displayed genotypes were determined using PCR screening, except for 19529, which did not produce any amplicons and whose genotype remains unknown. Lab ID (Fcat) numbers are presented under each individual in the pedigree.