Fig. 6. Superposition of atomistic models of Bvht 5′ module with experimental structure (yellow mesh).

a Ensemble of simulated structures of the five top χ ranked atomistic models of Bvht 5′ module (blue mesh) superimposed with SAXS structure (yellow mesh). b Five top χ ranked atomistic models of Bvht 5′ module at 6 mM Mg²⁺ (cyan to dark blue gradient). As in the full-length Bvht, atoms outside of SAXS-derived solution structure may indicate flexible regions. Most of this “flexible” region is the 11-nucleotide region (colored red) in the RHT/AGIL motif known to be essential to bind CNBP³. See Supplementary Movie 3 for more information.