Table 2.

Summary of IC₅₀s for pharmacological inhibitors of T-type VGCCs on lymphatic contraction amplitude and frequency.

Drug	Species	LV location	IC50 for amplitude	IC50 for frequency
Mibefradil	Rat	Mesenteric	66 nM	423 nM
Ni2+	Rat	Mesenteric	248 µM	279 µM
	Mouse	IAL	66 µM	1287 µM
	Mouse	Popliteal	110 µM	452 µM
TTA-A2	Mouse	Popliteal	1.3 µM	nd

nd = not-determined.