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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Struct Biol. 2019 Nov 11;209(1):107416. doi: 10.1016/j.jsb.2019.107416

Figure 2. Separating mixtures of synthetic 2D reprojections.

Figure 2.

Synthetic reprojections were generated from 35 distinct PDB structures low-pass filtered to 9 Å from protein and protein assemblies ranging in molecular weight from ~30 – 3000 kDa, prior to separation using SLICEM. (A) Low-pass filtered models of each PDB structure. (B) Precision-recall plot ranking 6 different metrics at scoring the similarity between 1D line projections from each 2D reprojection. (C) Distribution of scores calculated using Euclidean distance for reprojections belonging to the same structure and reprojections belonging to different structures.