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Schematic representation of cAMP formation/degradation and of cAMP target proteins. POPDC, Popeye domain containing protein, AC, adenylyl cyclase; Gs, stimulatory G protein; Gi, inhibitory G protein. CNGC, cyclic nucleotide-gated channels; EPAC, exchange protein directly activated by cAMP; Rap-GTP, GTP-binding Ras related protein; AKAP, A-kinase anchoring proteins; PDE, phosphodiesterase; PKA, cAMP-dependent protein kinase.
