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. 2019 Dec 17;8(12):1659. doi: 10.3390/cells8121659

Figure 4.

Figure 4

Enhanced secretion of IL-1Ra, soluble human leukocyte antigen G (sHLA-G) and tumor necrosis factor-inducible gene (TSG)-6 by ASCs of patients with rheumatic diseases (RD). Culture conditions of ASC lines from healthy donors (HD; n = 10), systemic lupus erythematosus (SLE; n = 12–16), systemic sclerosis (SSc; n = 10–17) and ankylosing spondylitis (AS; n = 9–15) patients were the same as described in Figure 3. Concentrations of indicated factors were measured in culture supernatants. Data are expressed as the Tukey’s boxes (see Figure 1). No differences between untreated (C) and cytokine-stimulated cells were found. # p = 0.05–0.01; ## p = 0.01–0.001; ### p = 0.001–0.0001; #### p < 0.0001 for HD/ASCs versus RD/ASCs comparison.