Figure 5.

Similar secretion of other factors by ASCs of healthy donors and patients with rheumatic diseases. Culture conditions of ASC lines from healthy donors (HD; n = 10) and from patients with rheumatic diseases (RD), i.e., systemic lupus erythematosus (SLE; n = 16), systemic sclerosis (SSc; n = 16–17) and ankylosing spondylitis (AS; n = 15), were the same as described in Figure 3. Concentrations of indicated factors were measured in culture supernatants. Data are expressed as the Tukey’s boxes (see Figure 1). * p = 0.05–0.01, *** p = 0.001–0.0001 for untreated (C) versus cytokine-treated cells; ^# p = 0.05–0.01, ^## p = 0.01–0.001 for HD/ASCs versus RD/ASCs.