Figure 6.

Vascularization inside the assembled RSUIM device. (a) Schematic and prototype of the assembled pasting-based RSUIM device with two medium reservoir modules. (b) Schematic and prototype of two assembled modular devices with the serial connection mode. (c) Simulation results of the uniform interstitial flow profile inside the tissue chambers of the generic vascularized organ-on-a-chip with coupling design. (d) Formation of fluorescent microvascular network inside the tissue chamber and its corresponding simulation results on the pressure distribution, velocity profile, and shear stress inside the vessel lumen, respectively.