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TTP knockdown in B-LCL#5. (A). Western blot performed with anti-TTP for the assessment of protein depletion 48 h after silencing with siCtlr or siTTP nucleofection. (B) Cytofluorimetric analysis of HLA-DQ surface expression, reported as fold change of MFI (Mean Fluorescence Intensity). (C) Fold variation of DRA, DRB1, DQA1, DQB1, and HLA-A, -B, and -C (class I) mRNAs. (D) Fold variation of DQA1*01, DQA1*05, DQB1*02, and DQB1*05 mRNAs.
