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Two types of cellular plasticity—dedifferentiation and transdifferentiation. Adipocytes are derived from multipotent mesenchymal stem cells, which can also give rise to fibroblasts, osteoblasts, and other cell types, such as muscle cells and chondrocytes (not shown). Adipocyte dedifferentiation into a preadipocyte and a mesenchymal stem cell, as well as transdifferentiation into a fibroblast are indicated with arrows.
