Applications of flexible microfluidics. The left side illustrates applications in flexible wearable electronics. The right side illustrates the applications in biological devices. (a–c) Pressure tactile sensors. Adapted with permission from Yeo, et al. [27]. (d) Flexible microfluidic shear force sensor wrapped around an artificial fingertip for shear measuring. Adapted with permission from Yin, et al. [81]. (e,f) Flexible microfluidic sweat sensor fabricated from several layers. Adapted with permission from Kim, et al. [177]. (g) Microfluidic wearable temperature sensor placed on the skin. Adapted with permission from Yoon, et al. [180]. (h,i) Microfluidic-based flexible stretchable circuits. Adapted with permission from Alfadhel, et al. [176]. (j) Flexible conductive microfluidic circuit. Adapted with permission from Sun et al. [181]. (k,l) Artificial placenta-type blood oxygenator based on flexible microfluidics. Adapted with permission from Dabaghi et al. [48]. (m,n) Elastomeric multidimensional microchannel inspired by blood vessels. Adapted with permission from Wu, et al. [185]. (o–q) Flexible PDMS microchannels integrated with polymeric nanopillars covered with gold nanodisks and fibroblasts spreading on them. Adapted with permission from Solis-Tinoco, et al. [46]. (r) Represents a microfluidic-based flexible neural probe. Adapted with permission from Minev et al. [189].