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Detection of binding kinetics of BMP-6 to gold surface via the MU-NHS linker. (1 and 2) QCM frequency and dissipation monitoring of BMP-6 binding to gold coated quartz crystals over time. Gold coated QCM crystals presenting the MU-NHS linker are (1) incubated with BMP-6 and then blocked with BSA or (2) blocked with BSA alone. The presence of the growth factor is further validated by the binding of anti-BMP-6 antibody.
