Oncogenic miRNAs
|
miR-182 |
PFN1 |
Promotes TNBC cell proliferation |
[115] |
miR-21 |
PTEN |
Promotes TNBC cell proliferation |
[90] |
miR-206 |
RASA1, SPRED1 |
Promote TNBC cell proliferation |
[47] |
miR-146a/146b-5p |
BRCA1 |
Increases BRCA1-mediated proliferation |
[146] |
miR-498 |
BRCA1 |
Promotes TNBC cell proliferation |
[147] |
miR-25-3p |
BTG2 |
Promotes TNBC cell proliferation |
[148] |
miR-20a-5p |
RUNX3, Bim, p21 |
Promote TNBC cell proliferation |
[149] |
miR-135b |
APC |
Promotes proliferation and metastasis |
[150] |
miR-502 |
STE8 |
Promotes cell proliferation and cell cycle |
[25] |
Oncosuppressor miRNAs
|
miR-203 |
BIRC5, LASP1 |
Suppress cell proliferation and migration |
[151] |
miR-205 |
ErbB3, VEGF-A, E2F1, LAMC1 |
Inhibit cell proliferation, cell invasion, cell cycle arrest, clonogenic potential |
[152,153] |
miR-200c |
XIAP |
Inhibits proliferation, induces apoptosis |
[126] |
miR-34a |
Notch-1, ErbB2, c-SRC |
Inhibit cell growth and invasion, activate senescence, sensitize to dasatinib |
[154,155,156] |
miR-940 |
ZNF24 |
Inhibits cell proliferation and migration |
[157] |
miR-211-5p |
SETBP1 |
Inhibits cell proliferation and migration |
[158] |
miR-1301 |
EZH2 |
Suppresses proliferation, migration, and colony formation |
[159] |
miR-146a-5p |
SOX5 |
Inhibits the proliferation and metastasis |
[136] |
miR-26a |
MTDH |
Suppresses tumor proliferation and metastasis |
[144] |
miR-490-3p |
TNKS2 |
Inhibits the growth and invasiveness |
[160] |
miR-143-3p |
LIMK1 |
Suppresses the growth |
[161] |
miR-17-5p |
ETV1 |
Suppresses cell proliferation and invasion |
[162] |
miR-539 |
LAMA4 |
Inhibits proliferation and migration |
[163] |
miR-125b |
MAP2K7 |
Inhibits proliferation |
[164] |
miR-217 |
KLF5 |
Inhibits cell growth, migration |
[165] |
miR-589 |
MTA2 |
Decreases cell proliferation, migration, and invasion |
[166] |