. Author manuscript; available in PMC: 2020 Jun 1.

Published in final edited form as: Ann Neurol. 2019 Jun;85(6):801–811. doi: 10.1002/ana.25486

Table 2.

TMEM106B rs1990622 genotype frequencies among neurologically normal controls (NC) and neurodegenerative disease groups. Reported as N (% of disease group). MAF = minor allele frequency. Results shown for association testing between TMEM106B rs1990622 genotype and disease state (relative to NC) by Cochran-Armitage trend tests. PD=Parkinson’s disease, FTD=Frontotemporal dementia, MCI=Mild cognitive impairment, AD=Alzheimer’s disease, ns=nonsignificant.

		NC	FTD		PD		MCI		AD

rs1990622	TT	37(27)	56(31)	ns	54(30)	ns	25(33)	ns	87(29)	ns
	TC	65(47)	89(50)		92(51)		35(47)		147(49)
	CC	35(26)	34(19)		33(19)		15(20)		66(22)

	MAF	0.49	0.44		0.44		0.43		0.47