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. 2019 Feb 20;2019(2):CD013272. doi: 10.1002/14651858.CD013272

Ledgerwood 2015.

Trial name or title Sequential Multiple Assignment Randomized Trial (SMART)
Methods Two‐phase randomized controlled trial
Participants Current adult smokers enrolled in an HIV clinic with a diagnosis of HIV/AIDS
Interventions Phase 1: participants are randomized to receive either standard care (brief counselling and bupropion) or standard care and entry into a prize draw (contingency management)
Phase 2a: non‐responders from Phase 1 are randomized to receive continued counselling and monitoring support, with or without a prize draw
Phase 2b: responders from Phase 1 are randomized to receive either no additional treatment, or continued monitoring + a prize draw
Outcomes Primary outcomes: urinary cotinine, longest duration of continuous abstinence, 7‐day self‐reported point prevalence, carbon monoxide at follow‐up times up to 12 months
Starting date August 2013
Contact information Lisa Sulkowski, Wayne State University (lsulkows@med.wayne.edu)
 David Ledgerwood, Wayne State University
Notes