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. 2019 Oct 18;2019(10):CD001233. doi: 10.1002/14651858.CD001233.pub3

Comparison 22. Laminaria tent versus intracervical prostaglandin E2: all women.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Uterine hyperstimulation with FHR changes 2 350 Risk Ratio (M‐H, Fixed, 95% CI) 0.17 [0.02, 1.42]
2 Caesarean section 5 920 Risk Ratio (M‐H, Fixed, 95% CI) 1.16 [0.93, 1.45]
3 Serious neonatal morbidity/perinatal death 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 3.16 [0.13, 76.70]
4 Serious maternal morbidity or death 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 0.35 [0.01, 8.52]
5 Cervix unfavourable/unchanged after 12‐24 hours 2 218 Risk Ratio (M‐H, Random, 95% CI) 0.46 [0.11, 1.96]
6 Oxytocin augmentation 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 1.41 [1.21, 1.64]
7 Uterine hyperstimulation without FHR changes 2 601 Risk Ratio (M‐H, Fixed, 95% CI) 0.17 [0.02, 1.36]
8 Uterine rupture 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 0.35 [0.01, 8.52]
9 Instrumental vaginal delivery 3 424 Risk Ratio (M‐H, Fixed, 95% CI) 1.05 [0.65, 1.69]
10 Apgar score < 7 at 5 minutes 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 5.28 [0.63, 44.30]
11 Neonatal intensive care unit admission 2 259 Risk Ratio (M‐H, Fixed, 95% CI) 1.58 [0.58, 4.33]
12 Perinatal death 1 185 Risk Ratio (M‐H, Fixed, 95% CI) 3.16 [0.13, 76.70]
13 Maternal side effects 1 165 Risk Ratio (M‐H, Fixed, 95% CI) 0.20 [0.01, 4.15]
14 Postpartum haemorrhage 2 239 Risk Ratio (M‐H, Fixed, 95% CI) 1.14 [0.46, 2.81]
15 Chorioamnionitis 1 74 Risk Ratio (M‐H, Fixed, 95% CI) 3.17 [0.35, 29.06]
16 Endometritis 2 490 Risk Ratio (M‐H, Random, 95% CI) 0.30 [0.08, 1.09]
17 Fetal distress 2 128 Risk Ratio (M‐H, Fixed, 95% CI) 0.44 [0.07, 2.90]