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. 2019 Oct 18;2019(10):CD001233. doi: 10.1002/14651858.CD001233.pub3

Comparison 39. Any mechanical method and oxytocin versus low dose misoprostol alone: all women (not pre‐specified).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Vaginal delivery not achieved in 24 hours 2 362 Risk Ratio (M‐H, Fixed, 95% CI) 0.48 [0.37, 0.63]
2 Uterine hyperstimulation with FHR changes 3 1463 Risk Ratio (M‐H, Fixed, 95% CI) 0.43 [0.17, 1.11]
3 Caesarean section 5 1779 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.80, 1.12]
4 Serious neonatal morbidity/perinatal death 2 1263 Risk Ratio (M‐H, Fixed, 95% CI) 0.82 [0.18, 3.65]
5 Oxytocin augmentation 2 336 Risk Ratio (M‐H, Random, 95% CI) 3.89 [0.70, 21.72]
6 Uterine hyperstimulation without FHR changes 3 498 Risk Ratio (M‐H, Fixed, 95% CI) 0.52 [0.30, 0.92]
7 Epidural analgesia 1 162 Risk Ratio (M‐H, Fixed, 95% CI) 1.07 [0.90, 1.27]
8 Meconium‐stained liquor 2 362 Risk Ratio (M‐H, Fixed, 95% CI) 0.72 [0.43, 1.19]
9 Apgar score < 7 at 5 minutes 1 162 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.20, 4.58]
10 Neonatal intensive care unit admission 4 1599 Risk Ratio (M‐H, Fixed, 95% CI) 0.66 [0.49, 0.90]
11 Perinatal death 2 1263 Risk Ratio (M‐H, Fixed, 95% CI) 0.82 [0.18, 3.65]
12 Women not satisfied 1 866 Risk Ratio (M‐H, Fixed, 95% CI) 1.68 [1.47, 1.93]
13 Maternal fever 2 298 Risk Ratio (M‐H, Fixed, 95% CI) 0.13 [0.04, 0.50]
14 Chorioamnionitis 1 200 Risk Ratio (M‐H, Fixed, 95% CI) 0.65 [0.32, 1.31]
15 Fetal distress 2 362 Risk Ratio (M‐H, Fixed, 95% CI) 0.55 [0.25, 1.21]