Khamaiseh 2012.

Methods	RCT
Participants	Inclusion criteria: age 15 years or more, term, singleton, live fetus in vertex presentation, intact membranes and BS < 6. Exclusion criteria: previous CS or history of other uterine surgery, history of ante partum haemorrhage, cephalopelvic disproportion, acute fetal distress revealed by a non stress test prior to induction, signs of infection, ruptured membranes, EFW > 4300, or known allergy to PG
Interventions	PG E2 (n = 204) tablets 3 mg, max 2 dose. AROM performed if labour did not commence after 2 doses Foley catheter (n = 210): 22/24F, 50‐60 mL in balloon.Removed after 24 hours and AROM if possible
Outcomes	Mode of delivery, time interval between the start of induction and delivery, oxytocin requirement, the indications for CS and adverse neonatal and maternal reactions to the cervical ripening agent. Hyperstimulation with and without FHR changes, failed induction.
Notes	Setting: King Hussein Medical Centre and Prince Ali Bin Al‐Hussein hospital, Jordan Study period: July 2009 ‐ July 2010 Funding: not reported Declarations of interest: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random sequence generated by computer
Allocation concealment (selection bias)	Unclear risk	Not described, only description: Randomisation was done by a computer‐generated list of random numbers
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not feasible due to nature of intervention
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not reported
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	ITT analysis not reported and not clear if used, no missing data or cases
Selective reporting (reporting bias)	Low risk	All pre‐specified outcomes were reported in results
Other bias	Low risk	No other bias detected