Skip to main content
. 2019 Oct 18;2019(10):CD001233. doi: 10.1002/14651858.CD001233.pub3

Tabowei 2003.

Methods Random number table, opaque sealed envelopes.
Participants Term pregnancy, singleton fetus in cephalic presentation, BS < 4.
Exclusion: ruptured membranes, placenta praevia, non‐reactive non‐stress test, EFW > 4000 g, prior uterine incision, parity > 4, contraindication to PGs.
Interventions Foley 50 mL max 12 hours (n = 61).
Vaginal misoprostol 25 mcg every 4 hours, max 6 doses (n = 60).
Outcomes Failure to achieve ripening within 12 hours, vaginal delivery within 24 hours, need for oxytocin augmentation, CS rate, tachysystole, hypertonus, meconium, maternal and neonatal complications, AS < 7, NICU admissions, febrile morbidity.
Notes Prior uterine incision is exclusion criterion, but 18 women with previous CS included.
Setting: Zonal general hospital, Nigeria
Study period: June 1998 to May 2001
Funding: not reported
Declarations of interest: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random number table.
Allocation concealment (selection bias) Low risk Opaque sealed envelopes.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not feasible due to nature of intervention
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Incomplete outcome data were not mentioned in the report.
Selective reporting (reporting bias) Low risk All outcomes prespecified in methods were reported, report includes all expected outcomes.
Other bias Unclear risk Prior uterine incision is exclusion criterion, but 18 women with previous CS included, they were evenly divided between the groups.