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. 2019 Jun 4;2019(6):CD013163. doi: 10.1002/14651858.CD013163.pub2
Decision matrix
for inconsistency
Heterogeneity I²> 40% (40% to 74%) Unexplained high heterogeneity
with I²> 75%and very low P value
Same direction of effect estimates in the studies May not downgrade 1 level if most of the studies have similar point estimates and overlapping CI AND all point estimates are pointing in the same direction. Downgrade 1 level
Different direction of effect estimates in the studies Downgrade 1 level Downgrade 2 levels