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. 2019 Jun 4;2019(6):CD013163. doi: 10.1002/14651858.CD013163.pub2
Study Reason for exclusion
Angsten 2002 Included term infants. Population included 36‐ to 41‐week newborn infants ≤ 4 days of age needing surgery and expected to require total PN for ≥ 5 days.
Ariyawangso 2014 Included newborn infants requiring surgery and term infants. Infants were randomised to receive SMOFlipid 20% (experimental group, n = 21) or Intralipid 20% (control group, n = 21).
Lima 1988 Included term infants up to 38 weeks' gestation.
Magnusson 1997 Included newborn infants requiring surgery and term infants.
Webb 2008 Included term infants with mean gestation of infants 37.0 (SD 3.6) weeks and 36.7 (SD 3.0) weeks in the 2 arms of the study.
Wilson 1997 Compare "aggressive parenteral nutrition" in preterm infants vs "conventional parenteral nutrition." The "aggressive nutrition group" received a higher rate of lipids, proteins, dextrose and 33% of participants in this group received insulin besides getting medium chain and long chain triglyceride‐based LE (Lipofundin). The conventional nutrition group received a lesser percentage of dextrose, lesser rate of lipids (S‐LE) and no insulin. The duration of LE was a median of 20 days (interquartile range 12 to 28 days) in the aggressive nutrition (MS‐LE) group vs a median of 6 days (interquartile range 2–15 days) in the conventional nutrition (S‐LE group). This study, done in 1997, reported advantages of the aggressive PN regimen vs conventional PN.

MS‐LE: medium‐chain triglyceride‐soybean oil lipid emulsion; n: number of participants; PN: parenteral nutrition; S‐LE: soybean oil‐based lipid emulsions; SD: standard deviation.