Comparison 3. Combined FFT & CWD vs sequential FFT‐CWD; Combined FFT & CSD vs sequential CWD‐FFT.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Depression ‐ CDRS‐R: end of treatment	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
2 Depression ‐ CDRS‐R: 12‐month follow‐up	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
3 Substance use ‐ square root % daily use: end of treatment	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
4 Substance use ‐ square root % daily use: 12‐month follow‐up	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
5 Premature termination	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
6 Treatment attendance	1		Mean Difference (IV, Random, 95% CI)	Subtotals only