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. 2020 Jan 9;8:2. doi: 10.1186/s40364-020-0182-y

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Potential neo-substrates of thalidomide, lenalidomide, pomalidomide, CC-122 and CC-220. Solid spheres represent potential neo-substrates. Spheres with crosses inside represent proteins that were not degraded by the corresponding compound, at least under the condition described in the references. Hollow spheres represent undetermined proteins. The five compounds were shown in different colors, as indicated. Thal, thalidomide. Len, lenalidomide. Pom, pomalidomide