Comparison 4. Ibuprofen vs NSAIDs.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain relief: dichotomous outcome	2		Odds Ratio (Fixed, 95% CI)	0.94 [0.55, 1.61]
1.1 Ibuprofen vs piroxicam	1		Odds Ratio (Fixed, 95% CI)	0.97 [0.53, 1.77]
1.2 Ibuprofen vs lysine clonixinate	1		Odds Ratio (Fixed, 95% CI)	0.84 [0.26, 2.69]
2 Pain relief continuous data: final pain relief score difference (time‐weighted TOPAR‐6 scale)	1		Mean Difference (Fixed, 95% CI)	Subtotals only
2.1 Ibuprofen vs etoricoxib TOPAR 6 difference (time‐weighted scale)	1		Mean Difference (Fixed, 95% CI)	‐0.89 [‐1.74, ‐0.04]
3 All adverse effects	2		Odds Ratio (Fixed, 95% CI)	1.38 [0.68, 2.80]
3.1 Ibuprofen vs fenoprofen	1		Odds Ratio (Fixed, 95% CI)	1.51 [0.72, 3.17]
3.2 Ibuprofen vs etoricoxib	1		Odds Ratio (Fixed, 95% CI)	0.50 [0.04, 5.88]
4 Additional analgesics required	3		Odds Ratio (Fixed, 95% CI)	1.07 [0.44, 2.60]
4.1 Ibuprofen vs fenoprofen	1		Odds Ratio (Fixed, 95% CI)	0.83 [0.21, 3.26]
4.2 Ibuprofen vs piroxicam	1		Odds Ratio (Fixed, 95% CI)	0.83 [0.21, 3.26]
4.3 Ibuprofen vs etoricoxib	1		Odds Ratio (Fixed, 95% CI)	4.10 [0.45, 37.25]