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. 2019 Nov 25;2019(11):CD013243. doi: 10.1002/14651858.CD013243.pub2

Comparison 1. Animal‐assisted therapy (AAT) versus no AAT.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Affect and emotional well‐being: depression measured using Cornell Scale for Depression in Dementia (CSDD) 2 83 Mean Difference (IV, Random, 95% CI) ‐2.87 [‐5.24, ‐0.50]
1.1 Individually randomised trial 1 37 Mean Difference (IV, Random, 95% CI) ‐3.55 [‐6.87, ‐0.23]
1.2 Cluster RCT 1 46 Mean Difference (IV, Random, 95% CI) ‐2.17 [‐5.54, 1.20]
2 Affect and emotional well‐being: apathy, measured using Apathy Evaluation Scale (AES) 1 37 Mean Difference (IV, Random, 95% CI) 1.81 [‐0.58, 4.20]
3 Affect and emotional well‐being: depressed or anxious mood, measured using Multidimensional Observation Scale for Elderly Subjects (MOSES) Depressed or Anxious Mood subscale 1 58 Mean Difference (IV, Random, 95% CI) ‐0.30 [‐3.52, 2.92]
4 Social functioning: MOSES Withdrawn Behaviour subscale 1 58 Mean Difference (IV, Random, 95% CI) ‐0.40 [‐3.41, 2.61]
5 Behaviour: measured using Nursing Home Behaviour Problem Scale (NHBPS), Neuropsychiatric Inventory (NPI), or MOSES Disoriented Behaviour subscale 3 142 Std. Mean Difference (IV, Random, 95% CI) ‐0.34 [‐0.98, 0.30]
5.1 AAT using horse 1 16 Std. Mean Difference (IV, Random, 95% CI) ‐1.24 [‐2.34, ‐0.14]
5.2 AAT using dog 2 126 Std. Mean Difference (IV, Random, 95% CI) ‐0.10 [‐0.64, 0.44]
6 Agitation: measured using Cohen‐Mansfield Agitation Inventor (CMAI), Brief Agitation Rating Scale (BARS), or MOSES Irritability subscale 3 143 Std. Mean Difference (IV, Random, 95% CI) ‐0.39 [‐0.89, 0.10]
6.1 Individually randomised trial 2 95 Std. Mean Difference (IV, Random, 95% CI) ‐0.62 [‐1.04, ‐0.21]
6.2 Cluster‐randomised controlled trial (RCT) 1 48 Std. Mean Difference (IV, Random, 95% CI) 0.08 [‐0.49, 0.64]
7 Quality of life (Quality of Life in Late‐Stage Dementia (QUALID)) 3 164 Mean Difference (IV, Random, 95% CI) 0.45 [‐1.28, 2.18]
7.1 Individually randomised trial 1 68 Mean Difference (IV, Random, 95% CI) ‐0.39 [‐3.57, 2.79]
7.2 Cluster‐RCT 2 96 Mean Difference (IV, Random, 95% CI) 0.44 [‐2.53, 3.41]
8 Physical functioning, measured using Barthel Index for ADL 1 37 Mean Difference (IV, Random, 95% CI) 4.65 [‐16.05, 25.35]
9 Physical functioning: balance, measured using Berg's Balance Scale 1 52 Mean Difference (IV, Random, 95% CI) ‐2.29 [‐5.66, 1.08]
10 Physical functioning: self‐care ability measured using MOSES Self‐Care Functioning subscale 1 58 Mean Difference (IV, Random, 95% CI) 2.20 [‐1.23, 5.63]