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. 2015 Jun 18;2015(6):CD010856. doi: 10.1002/14651858.CD010856.pub2

Tabari 2000.

Methods FLUOROSIS STUDY
Country of study: UK
Geographic location: Northumberland and Newcastle upon Tyne
Year of study: 1998
Year of change in fluoridation status: 1969
Study design: cross‐sectional
Participants Inclusion criteria: parental consent; lifetime residency
Exclusion criteria: not stated
Ethnicity: not stated
Other sources of fluoride: data on the use of fluoride drops and tablets collected but not presented. Data on toothbrushing habit/frequency presented in detail and appeared to be similar in F and non‐F areas
Social class: the subjects from Newcastle tended to reside in more underprivileged areas than those in Northumberland. The mean Jarman UPA8 score was 16.3 (SD = 19.1) for subjects in Newcastle and 7.3 (SD = 15.0) for Northumberland (P value < 0.001). However, the authors were reported to have chosen schools to provide children from a spectrum of SES backgrounds
Residential history: lifetime residents
Other confounding factors: not stated
Interventions Group 1: 1 ppm (artificial fluoridation)
 Group 2: 0.1 ppm (natural fluoridation)
Outcomes Dental fluorosis (TF Index);
Age at assessment: 8‐9 years
Funding Not stated
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Sampling Unclear risk In Newcastle and Northumberland, 14 and 15 schools respectively were chosen. However, there was insufficient information on how the selection was done
Confounding High risk There was a significant difference in measure of deprivation between the 2 study areas
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Assessment was by the use of photographs in order to allow examination of teeth of children without the examiner being aware of which area the child was from
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk In the 2 groups, 78% and 79% of the eligible children had complete data. It was not clear whether those whose photographs were unacceptable (examined but not analysed) were systematically different from those who remained in the study
Selective reporting (reporting bias) Low risk Outcome of interested reported
Other bias Low risk No other apparent bias