Comparison 3. PEP compared with HFCWO.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in FEV1 (% predicted)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
1.1 1 year	1	88	Mean Difference (IV, Fixed, 95% CI)	‐3.59 [‐9.29, 2.11]
2 Participants experiencing a respiratory exacerbation	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 1 year	1	91	Risk Ratio (M‐H, Fixed, 95% CI)	0.73 [0.55, 0.95]
3 Change in FVC (% predicted)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
3.1 1 year	1	88	Mean Difference (IV, Fixed, 95% CI)	‐5.00 [‐10.30, 0.30]
4 Change in FEF25‐75 (% predicted)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
4.1 1 year	1	88	Mean Difference (IV, Fixed, 95% CI)	‐0.34 [‐12.54, 11.86]