Adverse effect |
Odds ratio; 95% CI; heterogeneity; N of studies, N of participants |
P value |
Abdominal pain |
OR 3.74, 95% CI 0.62 to 22.59; I2 = 0%; 2 studies, 178 participants |
P = 0.15 |
Ammonia increased |
OR 9.25, 95% CI 0.49 to 174.87; 1 study, 150 participants |
P = 0.14 |
Excitement |
OR 1.92, 95% CI 0.08 to 44.92; 1 study, 28 participants |
P = 0.68 |
Difficulty concentrating |
OR 0.01, 95% CI 0.00 to 0.15; 1 study, 28 participants |
P = 0.002 |
Difficulty waking in the morning |
OR 0.10, 95% CI 0.00 to 2.78; 1 study, 28 participants |
P = 0.18 |
Dyspepsia (Indigestion) |
OR 5.00, 95% CI 0.24 to 105.93; 1 study, 150 participants |
P = 0.30 |
Enuresis |
Not estimable |
N/A |
Gastritis |
OR 9.25, 95% CI 0.49 to 174.87; 1 study, 150 participants |
P = 0.14 |
Headache |
OR 1.07, 95% CI 0.44 to 2.61; I2 = N/A; 2 studies, 178 participants |
P = 0.88 |
Initial insomnia |
Not estimable |
N/A |
Irritability |
Not estimable |
N/A |
Nausea |
OR 0.13, 95% CI 0.02 to 1.06; 1 study, 150 participants |
P = 0.06 |
Outburst of anger |
OR 6.29, 95% CI 0.31 to 127.06; 1 study, 28 participants |
P = 0.23 |
Pharyngitis streptococcal |
OR 7.10, 95% CI 0.36 to 139.78; 1 study, 150 participants |
P = 0.20 |
Pharyngolaryngeal pain |
OR 0.48, 95% CI 0.04 to 5.41; 1 study, 150 participants |
P = 0.55 |
Rash |
OR 4.06, 95% CI 0.44 to 37.17; 1 study, 150 participants |
P = 0.22 |
Nasal congestion |
OR 0.38, 95% CI 0.06 to 2.37; I2 = 0%; 2 studies, 178 participants |
P = 0.30 |
Sedation |
OR 0.40, 95% CI 0.12 to 1.37; 1 study, 150 participants |
P = 0.14 |
Sadness |
OR 0.42, 95% CI 0.05 to 3.22; 1 study, 28 participants |
P = 0.40 |
Somnolence |
OR 5.14, 95% CI 0.59 to 45.10; 1 study, 150 participants |
P = 0.14 |
Upper respiratory tract infection |
OR 0.97, 95% CI 0.06 to 15.85; 1 study, 150 participants |
P = 0.98 |
Vomiting |
OR 1.72, 95% CI 0.59 to 4.99; 1 study, 150 participants |
P = 0.32 |
Weight increase |
OR 1.97, 95% CI 0.18 to 22.24; 1 study, 150 participants |
P = 0.58 |