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. 2019 Oct 7;2019(10):CD004052. doi: 10.1002/14651858.CD004052.pub2

21. Adverse events ‐ valproate vs quetiapine (children and adolescents).

Adverse effect Odds ratio; 95% CI; heterogeneity; N of studies, N of participants P value
Dizziness OR 1.00, 95% CI 0.32 to 3.17; 1 study, 50 participants P = 1.00
Dry mouth OR 0.28, 95% CI 0.05 to 1.53; 1 study, 50 participants P = 0.14
Gastrointestinal upset OR 0.81, 95% CI 0.23 to 2.88; 1 study, 50 participants P = 0.75
Increased appetite OR 1.57, 95% CI 0.24 to 10.30; 1 study, 50 participants P = 0.64
Insomnia OR 0.31, 95% CI 0.03 to 3.16; 1 study, 50 participants P = 0.32
Sedation or lethargy OR 0.38, 95% CI 0.12 to 1.18; 1 study, 50 participants P = 0.09