Adverse effect |
Odds ratio; 95% CI; heterogeneity; N of studies, N of participants |
P value |
Abdominal pain |
OR 14.49, 95% CI 0.54 to 389.63; I2 = 57%; 2 studies, 228 participants |
P = 0.11 |
Appetite increase |
OR 0.08, 95% CI 0.04 to 0.16; 1 study, 189 participants |
P < 0.001 |
Dry mouth/excessive thirst |
OR 0.44, 95% CI 0.23 to 0.85; 1 study, 189 participants |
P = 0.01 |
Enuresis |
OR 2.74, 95% CI 0.01 to 829.22; I2 = 87%; 2 studies, 228 participants |
P = 0.73 |
Excitement |
OR 4.74, 95% CI 0.21 to 105.54; 1 study, 39 participants |
P = 0.33 |
Fever |
OR 0.88, 95% CI 0.33 to 2.32; 1 study, 189 participants |
P = 0.79 |
Frequent urination |
OR 2.25, 95% CI 0.83 to 6.14; 1 study, 189 participants |
P = 0.11 |
Headache |
OR 0.06, 95% CI 0.00 to 1.12; 1 study, 39 participants |
P = 0.06 |
Initial insomnia |
OR 0.27, 95% CI 0.01 to 7.08; 1 study, 39 participants |
P = 0.43 |
Irritability |
OR 0.15, 95% CI 0.01 to 3.42; 1 study, 39 participants |
P = 0.24 |
Nasal congesion |
OR 1.38, 95% CI 0.72 to 2.64; I2 = 0%; 2 studies, 228 participants |
P = 0.33 |
Nausea |
OR 1.47, 95% CI 0.71 to 3.04; 1 study, 189 participants |
P = 0.29 |
Outburst of anger |
OR 2.00, 95% CI 0.42 to 9.52; 1 study, 39 participants |
P = 0.38 |
Rash |
OR 2.07, 95% CI 0.75 to 5.69; 1 study, 189 participants |
P = 0.16 |
Sadness |
OR 0.58, 95% CI 0.11 to 3.04; 1 study, 39 participants |
P = 0.52 |
Sedation |
OR 0.50, 95% CI 0.28 to 0.91; 1 study, 189 participants |
P = 0.02 |
Vomiting |
OR 1.45, 95% CI 0.54 to 3.91; 1 study, 189 participants |
P = 0.47 |
Weight gain |
OR 0.12, 95% CI 0.04 to 0.34; 1 study, 189 participants |
P < 0.001 |
Weight loss |
OR 3.63, 95% CI 1.61 to 8.19; 1 study, 189 participants |
P = 0.002 |