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. 2019 Oct 7;2019(10):CD004052. doi: 10.1002/14651858.CD004052.pub2

Comparison 13. Valproate vs placebo (sensitivity analysis treatment resistant mania removed).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Response rate (adults) 3   Odds Ratio (M‐H, Random, 95% CI) Subtotals only
1.1 at 3 weeks 3 826 Odds Ratio (M‐H, Random, 95% CI) 1.83 [1.31, 2.55]