Comparison 16. Valproate vs lithium (sensitivity analysis unclear blinding/allocation concealment removed).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Response rate (adults)	1		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Week 3	1	105	Odds Ratio (M‐H, Random, 95% CI)	1.02 [0.46, 2.30]
2 Number with any adverse effect (primary tolerability outcome)	1		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
2.1 Adults	1	105	Odds Ratio (M‐H, Random, 95% CI)	0.48 [0.12, 1.84]