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. 2019 Nov 13;2019(11):CD011116. doi: 10.1002/14651858.CD011116.pub3

Summary of findings 3. Laser for gagging in patients undergoing dental treatment.

Laser for gagging in patients undergoing dental treatment
Patient or population: patients undergoing dental treatment
Setting: university hospital
Intervention: laser
Comparison: control
Outcomes Anticipated absolute effects* (95% CI) Relative effect(95% CI) Number of participants(studies) Certainty of the evidence(GRADE) Comments
Risk with control Risk with laser
Completion of dental treatment None of the trials reported this outcome
Reduction in gagging
(assessor‐reported)
The mean reduction in gagging was 0 MD 1.80 higher
(1.53 higher to 2.07 higher)
25
(1 RCT)a ⊕⊝⊝⊝
VERY LOWc,d,f
Low‐level laser at P6 point for 14 seconds
Presence or absence of gagging Study population OR 86.33
(29.41 to 253.45) 40
(1 RCT)b ⊕⊝⊝⊝
VERY LOWc,d,e Low‐level laser at P6 point for 1 minute showed difference in absence of gagging
125 per 1000 925 per 1000
(808 to 973)
Adverse effects None of the trials reported adverse effects
*The risk in the intervention group (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI)

CI: confidence interval; MD: mean difference; OR: odds ratio; P6: point located 3‐finger breadths below the wrist on the inner forearm in between the 2 tendons; RCT: randomised controlled trial
GRADE Working Group grades of evidenceHigh certainty: we are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect

aElbay 2016.
bGoel 2017.
cDowngraded 1 level for unclear risk of bias.
dDowngraded 1 level for indirectness: single trial done only in children.
eDowngraded 1 level, imprecision apparent from width of confidence interval (due to small sample size (n = 40)).
fDowngraded 1 level, imprecision apparent from width of confidence interval (due to small sample size (n = 25)).