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. 2019 Nov 13;2019(11):CD011116. doi: 10.1002/14651858.CD011116.pub3

Hekmatian 2011b.

Methods Study design: unclear if randomised or non‐RCT
Country: Iran
Setting: radiology department of the School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
Period of trial: not mentioned
Participants Total number of participants (randomised?): 84
Age: mean age 24.6 ± 0.8 years
Gender: male = 42, female = 42
Inclusion criteria: patients admitted to the radiology department of the dentistry school; informed consent; no central or peripheral nervous system disorders or had any oral lesions; high co‐operation
Exclusion criteria: patients who suffered from any type of central or peripheral nervous system disorders; any oral lesions
Interventions Intervention: pomegranate peel extract lozenges (n = 42)
Control: placebo lozenges (n = 42)
Intervention details: "The patients sucked the lozenges in their mouth till it was completely dissolved. After five minutes, the patient felt senselessness in the soft palate and pharyngeal tonsil. The patient was then evaluated regarding the intensity and degree of gag reflex in the soft palate and pharyngeal tonsils"
Outcomes Outcomes reported:
  • reduction in gagging:

    • gag reflex in soft palate

    • gag reflex in pharyngeal tonsil

Notes Funding source: not mentioned
Sample size calculation: simple non‐probability sampling
Adverse effects: not mentioned
Attrition: nil
Trials registration: not registered
Notes: email sent for additional information regarding randomisation and nature of participants on 12 June 2014; no reply received