Jia 2005.

Methods	Parallel design Aim: to determine the effect of early intervention for post stroke depression on movement after 3 months of stroke
Participants	Country: China Setting: inpatient Inclusion: aged 40 to 75 years, all pathological types of stroke, clinical diagnosis plus confirmation by imaging (did not state whether a relevant lesion had to be present to make a diagnosis), able to give informed consent Depression diagnosis: Zung SDS > 41 for screening for depression, HDRS for evaluation of the depression severity level Treatment: 92 people randomised, 90 accepted allocation, mean age 55.6 ± 6.5 years, 60 men Control: 92 people randomised, 90 accepted allocation, mean age 55.1 ± 6.8, 55 men Excluded: organic psychiatric disorders such as Alzheimer's disease or degenerative disease, functional disorders such as schizophrenia and affective disorders
Interventions	Treatment: either fluoxetine or sertraline (given sertraline if also had anxiety) plus routine stroke care Control: routine stroke care Duration of treatment: 3 months Duration of follow‐up: 3 years but the authors did not describe the extent of neurological function damage and HAMD scores in the third year
Outcomes	HAMD Extent of neurological damage Recurrent stroke Death Did not report AEs
Funding source	Source of funding not stated
Notes	−
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	No placebo
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	No blinding
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Dropouts: 6 in treatment group (2 refused allocation), 4 in control group (2 refused allocation)
Selective reporting (reporting bias)	Unclear risk	No protocol
Other bias	Unclear risk	Balanced baseline