Skip to main content
. 2019 Nov 26;2019(11):CD009286. doi: 10.1002/14651858.CD009286.pub3

Li 2005.

Methods Parallel design
Improvement of post‐stroke depression and augmentation of rehabilitation
Participants Country: China
Setting: inpatient
Stroke criteria: all stroke, clinical diagnosis plus confirmation on imaging (though not clear whether a relevant lesion had to be present)
Depression according to CCMD‐II‐R
Treatment: 74 participants
Control: 74 participants
Participaients in the treatment and control groups were selected from a group of 368 stroke patients with an average age of 57 ± 11.8 years, age range 33 to 84 years, 240 men
Excluded: previous psychiatric disorders, severe dementia, aphasia, consciousness disturbance
Interventions Treatment: paroxetine 20 mg daily plus routine stroke treatment
Control: routine stroke treatment
Duration of treatment: 4 weeks
Duration of follow‐up (end of treatment to study end): 0
Outcomes HAMD
SSS
Deaths
Side effects not recorded
Funding source Source of funding not stated
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomisation method not described
Allocation concealment (selection bias) Unclear risk No description
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No placebo
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not stated whether blinded
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Analysed according to allocated treatment group, no participant dropped out
Selective reporting (reporting bias) Unclear risk No protocol
Other bias Unclear risk No description of differences between treatment and control group