Li 2005.
Methods | Parallel design Improvement of post‐stroke depression and augmentation of rehabilitation |
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Participants | Country: China Setting: inpatient Stroke criteria: all stroke, clinical diagnosis plus confirmation on imaging (though not clear whether a relevant lesion had to be present) Depression according to CCMD‐II‐R Treatment: 74 participants Control: 74 participants Participaients in the treatment and control groups were selected from a group of 368 stroke patients with an average age of 57 ± 11.8 years, age range 33 to 84 years, 240 men Excluded: previous psychiatric disorders, severe dementia, aphasia, consciousness disturbance |
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Interventions | Treatment: paroxetine 20 mg daily plus routine stroke treatment Control: routine stroke treatment Duration of treatment: 4 weeks Duration of follow‐up (end of treatment to study end): 0 |
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Outcomes | HAMD SSS Deaths Side effects not recorded |
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Funding source | Source of funding not stated | |
Notes | − | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomisation method not described |
Allocation concealment (selection bias) | Unclear risk | No description |
Blinding of participants and personnel (performance bias) All outcomes | High risk | No placebo |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not stated whether blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Analysed according to allocated treatment group, no participant dropped out |
Selective reporting (reporting bias) | Unclear risk | No protocol |
Other bias | Unclear risk | No description of differences between treatment and control group |