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. 2019 Nov 26;2019(11):CD009286. doi: 10.1002/14651858.CD009286.pub3

Liu 2006.

Methods Parallel design
Aim: to study effect of citalopram on post‐stroke depression and neurological functional rehabilitation
Participants Country: China
Setting: inpatient
Stroke criteria: stroke during "recovery phase" at 6 to 9 months, NIHSS score ≥ 13, HAMD score ≥ 17
60 people randomised, of whom 38 were men, mean age 60.7 ± 8.6 years. Demographics for treatment and control groups were not provided
Treatment: 30 people, age and gender not stated
Control: 30 people, age and gender not stated
Exclusion criteria: previous psychiatric disorder, dementia, aphasia, consciousness disturbance
Interventions Treatment: citalopram 20 mg daily plus routine stroke care
Control: routine stroke care
Duration of treatment: 6 weeks
Duration of follow‐up (treatment end to study end): 0
Outcomes HAMD
NIHSS
BI
Death
Funding source Source of funding not stated
Notes AEs not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method not described
Allocation concealment (selection bias) Unclear risk Not described
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No placebo
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not stated
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No dropouts
Selective reporting (reporting bias) Unclear risk No protocol
Other bias Unclear risk Baseline balance reported by authors