Xie 2005.

Methods	Aim: to study the effect of treatment with sertraline in elderly patients with post‐stroke depression Parallel study
Participants	Country: China Setting: unclear Recruited "clinically stable stroke patients with post‐stroke depression" No other inclusion and exclusion criteria given Mood: Zung SDS score ≥ 40 or GDS score 5 to 10 Treatment: 65 people, mean age 69.8 years, 29 men Control: 65 people, mean age 70.7 years, 27 men Time since stroke: mean 87.8 days, range 48 to 142 days
Interventions	Treatment: sertraline 50 mg/day plus usual stroke care Control: usual stroke care Duration of treatment: 12 weeks Duration of follow‐up: 0
Outcomes	Zung SDS, GDS, ADL score AEs were not reported
Funding source	Local scientific academic fund funded the study
Notes	−
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	No placebo
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropouts
Selective reporting (reporting bias)	Unclear risk	No protocol
Other bias	Unclear risk	No clear description between treatment and control