Karimialavijeh 2017.

Trial name or title	Comparison of the effects of citalopram versus fluoxetine on motor recovery after stroke: a double‐blind placebo‐controlled randomised clinical trial
Methods	Study type: interventional (clinical trial) Estimated enrolment: 90 participants Allocation: randomised Intervention model: parallel assignment Masking: unclear Primary purpose: treatment
Participants	Iran (Islamic Republic of Iran) Inclusion criteria: Age > 18 years First‐time acute (in the past 24 hours) ischaemic stroke hemiparesis or hemiplegia FMMS score < 55 Exclusion criteria: NIHSS score < 5 Existing impairments including stroke‐related aphasia, cognitive or motor disorders, or other neurodegenerative disease Pregnancy or breastfeeding Using antidepressant medication Contraindications of therapy (e.g. renal insufficiency abnormal liver function tests) Signifcant adverse effects (e.g. agitation, hypertension) as a consequence of treatment
Interventions	Experimental: 20 mg of fluoxetine orally, daily for 90 days, as well as physiotherapy sessions 1 hour a day, 5 days a week, for 12 weeks Comparator 1: 20 mg of citalopram orally, daily for 90 days, as well as physiotherapy sessions 1 hour a day, 5 days a week, for 12 weeks Comparator 2: capsules containing microcrystalline cellulose, orally, daily for 90 days, as well as physiotherapy sessions 1 hour a day, 5 days a week, for 12 weeks
Outcomes	Primary outcome collected at 90 days Motor function (FMMS score)
Starting date	3 December 2017
Contact information	Ehsan Karimialavijeh Dr Shariati hospital, North Karegar Ave1411713135 Tehran Iran (Islamic Republic of) drkarimi86@gmail.com
Notes	IRCT20141116019971N3