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. 2019 Nov 26;2019(11):CD009286. doi: 10.1002/14651858.CD009286.pub3

Pirzeh 2012.

Trial name or title A study of sertraline effect on quality of life in stroke inpatients
Methods Study type: interventional (clinical trial)
Estimated enrolment: 80 participants
Allocation: randomised
Intervention model: parallel assignment
Masking: unclear
Primary purpose: prevention
Participants Iran (Islamic Republic of Iran)
Inclusion criteria:

  • 55 years old to 75 years old

  • first‐ever stroke


Exclusion criteria:

  • History of stroke

  • Renal failure

  • Hepatic failure

  • Cardiac failure

  • Substance related disorders


Aiming to recruit 80 participants
Interventions Experimental: 3 weeks after stroke sertraline 50 mg a day for 12 months versus
Comparator: 3 weeks after stroke a placebo tablet every day
Outcomes Primary outcomes collected at 3 months, 6 months, 9 months

  • Quality of life (NHP)


Secondary outcomes collected at 3 months, 6 months, 9 months

  • Depression (BDI)
Starting date 28 November 2012
Contact information Reza Pirzeh, Tabriz University of Medical Sciences, Iran (Islamic Republic of)
pirzehr@tbzmed.ac.ir
Notes IRCT2012101011062N1