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. 2018 May 15;2018(5):CD004829. doi: 10.1002/14651858.CD004829.pub4

Comparison 2. Conscious sedation + analgesia (CSA) versus other active interventions.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Intraoperative pain 2   Mean Difference (IV, Random, 95% CI) Subtotals only
1.1 CSA vs CSA + acupuncture (VAS 0 to 10) 1 62 Mean Difference (IV, Random, 95% CI) 1.0 [0.18, 1.82]
1.2 CSA vs CSA + electro‐acupuncture (VAS 0 to 10) 1 62 Mean Difference (IV, Random, 95% CI) 3.00 [2.23, 3.77]
1.3 CSA vs CSA + electro‐acupuncture (Pain scale 1 to 12) 1 316 Mean Difference (IV, Random, 95% CI) 1.70 [1.07, 2.33]
2 Postoperative pain 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.1 CSA vs CSA + acupuncture (VAS 0 to 10) 1 61 Mean Difference (IV, Fixed, 95% CI) 0.60 [‐0.10, 1.30]
2.2 CSA vs CSA + electro‐acupuncture (VAS 0 to 10) 1 61 Mean Difference (IV, Fixed, 95% CI) 2.1 [1.40, 2.80]
2.3 CSA vs general anaesthesia (Likert 0 to 3) 1 50 Mean Difference (IV, Fixed, 95% CI) ‐1.90 [‐2.24, ‐1.56]
3 Pregnancy 3   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
3.1 CSA vs CSA + acupuncture 1 61 Odds Ratio (M‐H, Fixed, 95% CI) 0.61 [0.20, 1.86]
3.2 CSA vs CSA + electro‐acupuncture 1 61 Odds Ratio (M‐H, Fixed, 95% CI) 0.22 [0.07, 0.66]
3.3 CSA vs general anaesthesia 2 108 Odds Ratio (M‐H, Fixed, 95% CI) 1.0 [0.43, 2.35]
4 Postop vomiting and/or vomiting 2   Odds Ratio (M‐H, Fixed, 95% CI) Totals not selected
4.1 CSA vs CSA + acupuncture 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
4.2 CSA vs general anaesthesia 1   Odds Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
5 Satisfaction 2   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
5.1 CSA vs general anaesthesia 2 108 Odds Ratio (M‐H, Fixed, 95% CI) 0.66 [0.11, 4.04]
6 Postoperative complications (airway obstruction) 1 58 Odds Ratio (M‐H, Fixed, 95% CI) 0.14 [0.02, 1.22]
6.1 CSA vs general anaesthesia 1 58 Odds Ratio (M‐H, Fixed, 95% CI) 0.14 [0.02, 1.22]
7 Postoperative complications (mask ventilation) 1 58 Odds Ratio (M‐H, Fixed, 95% CI) 0.05 [0.01, 0.20]
7.1 CSA vs general anaesthesia 1 58 Odds Ratio (M‐H, Fixed, 95% CI) 0.05 [0.01, 0.20]