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. 2018 May 15;2018(5):CD004829. doi: 10.1002/14651858.CD004829.pub4

Comparison 3. Conscious sedation + analgesia (CSA) + paracervical block versus other interventions.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Intraoperative pain (VAS 0 to 10) 4   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.1 CSA + paracervical block versus electro‐acupuncture + paracervical block 4 781 Mean Difference (IV, Fixed, 95% CI) ‐0.66 [‐0.93, ‐0.39]
2 Postoperative pain 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
2.1 CSA + paracervical block vs general anaesthesia 1 50 Mean Difference (IV, Fixed, 95% CI) 0.49 [‐0.13, 1.11]
2.2 CSA + paracervical block vs spinal anaesthesia 1 36 Mean Difference (IV, Fixed, 95% CI) 1.02 [0.48, 1.56]
3 Live birth or ongoing pregnancy 2 393 Odds Ratio (M‐H, Fixed, 95% CI) 1.20 [0.78, 1.86]
3.1 CSA + paracervical block vs electro‐acupuncture + paracervical block 1 149 Odds Ratio (M‐H, Fixed, 95% CI) 2.35 [1.09, 5.05]
3.2 CSA + paracervical block vs electro‐acupuncture + paracervical block 1 244 Odds Ratio (M‐H, Fixed, 95% CI) 0.86 [0.50, 1.47]
4 Pregnancy 7   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
4.1 CSA + paracervical block vs general anaesthesia 1 51 Odds Ratio (M‐H, Fixed, 95% CI) 0.70 [0.22, 2.26]
4.2 CSA + paracervical block vs spinal anaesthesia 1 38 Odds Ratio (M‐H, Fixed, 95% CI) 0.93 [0.24, 3.65]
4.3 CSA + paracervical block vs paracervical block only 1 150 Odds Ratio (M‐H, Fixed, 95% CI) 0.93 [0.44, 1.96]
4.4 CSA + paracervical block vs electro‐acupuncture + paracervical block 4 783 Odds Ratio (M‐H, Fixed, 95% CI) 0.96 [0.72, 1.29]
4.5 CSA + paracervical block vs CSA alone 1 100 Odds Ratio (M‐H, Fixed, 95% CI) 0.62 [0.28, 1.36]
5 Fertilisation rate per woman 1   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
5.1 CSA + paracervical block vs paracervical block only 1 150 Odds Ratio (M‐H, Fixed, 95% CI) 0.83 [0.42, 1.66]
6 Postoperative nausea and/or vomiting 2   Odds Ratio (M‐H, Fixed, 95% CI) Subtotals only
6.1 CSA + paracervical block vs CS only 2 140 Odds Ratio (M‐H, Fixed, 95% CI) 0.42 [0.18, 0.97]
7 Patient satisfaction by Likert scale: report of 'excellent and satisfactory' 1 150 Odds Ratio (M‐H, Fixed, 95% CI) 1.63 [0.68, 3.89]
7.1 CSA + paracervical block vs paracervical block only 1 150 Odds Ratio (M‐H, Fixed, 95% CI) 1.63 [0.68, 3.89]