Ng 2001.

Methods	Randomisation: computer‐generated Allocation concealment: sealed envelopes Blinding of participants/investigators: yes Blinding of assessors: yes No. randomised: 150 No. analysed: 150 Intention‐to‐treat analysis: yes Power and sample calculations described Duration of trial: not stated
Participants	Women undergoing egg collection Mean age: 35 years (range 27 to 43 years) Cause of infertility: tuboperitoneal, male factor, endometriosis, unexplained Similar demographic and infertility characteristics at baseline
Interventions	Control: conscious sedation and analgesia (placebo with normal saline) and PCB (N = 75) Intervention: conscious sedation and analgesia with (IV diazepam 5 mg and pethidine 25 mg) and PCB (10 mL lidocaine; 1.5%) (N = 75) Both groups received premedication (IM pethidine 50 mg and promethazine 25 mg)
Outcomes	Primary: intraoperative pain score (VAS 0 to 100) Secondary: pregnancy rates, fertilisation, patient satisfaction (excellent, satisfactory, fair, or unsatisfactory) Other outcomes reported: no. of embryos transferred, implantation rate, multiple pregnancy rate
Notes	China Single centre University of Hong Kong Funding: not stated Definition of pregnancy not documented
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated
Allocation concealment (selection bias)	Low risk	Adequate: sealed envelopes
Blinding (performance bias and detection bias) All outcomes	Low risk	Both participant and doctor carrying out the procedure were blind to the sedation given Nurses not involved in the Unit asked participants about pain levels
Incomplete outcome data (attrition bias) All outcomes	Low risk	No loss to follow‐up
Selective reporting (reporting bias)	Low risk	All prespecified outcomes reported
Other bias	Low risk	Comparable demographic and infertility characteristics at baseline