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. 2019 Oct 2;2019(10):CD003200. doi: 10.1002/14651858.CD003200.pub8

Comparison 2. Exercise therapy versus psychological treatment.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 Fatigue at end of treatment (FS; 11 items/0 to 33 points) 2   Mean Difference (IV, Random, 95% CI) Totals not selected
2.1.1 CBT 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.1.2 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.2 Fatigue at follow‐up (SMD) 2 351 Std. Mean Difference (IV, Random, 95% CI) 0.07 [‐0.13, 0.28]
2.3 Participants with serious adverse reactions 2   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.3.1 CBT 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.3.2 Suportive listening 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.4 Pain at follow‐up (Brief Pain Inventory, pain severity subscale; 0 to 10 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.4.1 CBT 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.4.2 Cognitive therapy 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.5 Pain at follow‐up (Brief Pain Inventory, pain interference subscale; 0 to 10 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.5.1 CBT 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.5.2 Cognitive therapy 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.6 Physical functioning at end of treatment (SF‐36, physical functioning subscale; 0 to 100 points) 2   Mean Difference (IV, Random, 95% CI) Totals not selected
2.6.1 CBT 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.6.2 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.7 Physical functioning at follow‐up (SF‐36, physical functioning subscale; 0 to 100 points) 3   Mean Difference (IV, Random, 95% CI) Subtotals only
2.7.1 CBT 2 348 Mean Difference (IV, Random, 95% CI) 7.92 [‐9.79, 25.63]
2.7.2 Cognitive therapy 1 47 Mean Difference (IV, Random, 95% CI) 21.37 [6.61, 36.13]
2.7.3 Supportive listening 1 171 Mean Difference (IV, Random, 95% CI) ‐7.55 [‐15.57, 0.47]
2.8 Quality of life (follow‐up) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.8.1 Quality of Life Scale (16 to 112 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.9 Depression at end of treatment (HADS depression score; 7 items/21 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.9.1 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.10 Depression at follow‐up (SMD) 2 331 Std. Mean Difference (IV, Random, 95% CI) 0.01 [‐0.21, 0.22]
2.11 Anxiety at end of treatment (HADS anxiety; 7 items/21 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.11.1 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.12 Anxiety at follow‐up (SMD) 2 331 Std. Mean Difference (IV, Random, 95% CI) 0.07 [‐0.15, 0.28]
2.13 Sleep at end of treatment (Jenkins Sleep Scale; 0 to 20 points) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.13.1 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.14 Sleep at follow‐up (Jenkins Sleep Scale; 0 to 20 points) 2   Mean Difference (IV, Random, 95% CI) Totals not selected
2.14.1 CBT 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.14.2 Supportive listening 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.15 Self‐perceived changes in overall health at end of treatment 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.15.1 CBT 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.16 Self‐perceived changes in overall health at follow‐up 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
2.16.1 Cognitive therapy 1 50 Risk Ratio (M‐H, Random, 95% CI) 0.62 [0.36, 1.10]
2.16.2 CBT 2 368 Risk Ratio (M‐H, Random, 95% CI) 0.71 [0.33, 1.54]
2.17 Health resource use (follow‐up) (Mean no. of contacts) 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.1 Primary care 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.2 Other doctor 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.3 Healthcare professional 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.4 Inpatient 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.5 Accident and emergency 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.6 Other health/social services 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.7 Complementary health care 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.17.8 Standardised medical care 1   Mean Difference (IV, Random, 95% CI) Totals not selected
2.18 Health resource use (follow‐up) (No. of users) 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.1 Primary care 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.2 Other doctor 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.3 Healthcare professional 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.4 Inpatient 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.5 Accident and emergency 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.6 Medication 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.7 Complementary health care 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.8 Other health/social services 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.18.9 Standardised medical care 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.19 Dropout 2   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.19.1 CBT 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
2.19.2 Supportive listening 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected