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. 2019 Nov 19;2019(11):CD012487. doi: 10.1002/14651858.CD012487.pub2

Summary of findings for the main comparison. Sit‐stand desk compared to no intervention for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers.

Sit‐stand desk compared to no intervention for increasing standing or walking for decreasing musculoskeletal symptoms in sedentary workers
Patient or population: sedentary workers with musculoskeletal symptoms
 Setting: office setting
 Intervention: sit‐stand desk
 Comparison: no intervention
Outcomes Anticipated absolute effects* (95% CI) Relative effect
 (95% CI) № of participants
 (studies) Certainty of the evidence
 (GRADE) Comments
Risk with no intervention Risk with sit‐stand desk
Mean difference in low back pain follow‐up short‐term   SMD 0.35 lower
 (0.8 lower to 0.1 higher) 79
 (2 RCTs) ⊕⊕⊝⊝
 Lowa,b  
Mean difference in upper back pain follow‐up short‐term   SMD 0.48 lower
 (0.96 lower to 0) 71
 (2 RCTs) ⊕⊕⊝⊝
 Lowa,b  
Mean difference in neck and shoulder pain/discomfort follow‐up short‐term Mean difference in neck and shoulder pain/discomfort follow‐up short‐term: 2.2 score MD 0.6 score lower
 (1.5 lower to 0.3 higher) 31
 (1 RCT) ⊕⊕⊝⊝
 Lowb,c  
Mean difference in physical disability caused by LBP, RMDQ score follow‐up short‐term Mean difference in physical disability caused by LBP, RMDQ score follow‐up short‐term: 5.67 score MD 0.4 score lower
 (2.7 lower to 1.9 higher) 46
 (1 RCT) ⊕⊕⊝⊝
 Lowa,b  
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 
 CI: confidence interval; LBP: low back pain; MD: mean difference; RCT: randomised controlled trial; RMDQ: Roland Morris Disability Questionnaire; SMD: standardised mean difference.
GRADE Working Group grades of evidence.High certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
 Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
 Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
 Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

aConcerns about blinding of personnel and outcome assessors as well as allocation concealment. Unacceptable loss to follow‐up in Ognibene (2016); downgraded one level.

bLow number of participants, wide confidence intervals; downgraded one level.

cConcerns about blinding of personnel and outcome assessors as well as random sequence generation; downgraded one level.